Thursday, October 17, 2024

The Pharmaceutical Industry by Ron Piana



Ronald Piana: Hydrogen peroxide is a well-established apoptosis-inducer with broad cytotoxic activity in a range of cell types. Other H2O2 cytotoxic pathways have been identified, such as lysosomal membrane permeabilization (LMP). In LMP, the lysosome (described as a “suicide bag”) is compromised by H2O2-driven oxidative stress, during which large amounts of H2O2 enter the lysosomal compartment, forming abundant hydroxyl radicals, or highly reactive iron-centered radicals, which leads to degradation of cellular structures and, ultimately, cell death. Yet another intriguing explanation considers the Warburg effect, wherein transformed cells, such as those in cutaneous malignancies, undergo a shift from oxidative to glycolytic metabolism, rendering cells more susceptible to H2O2-induced oxidative stress. H2O2 has other cytotoxic pathways, yet, in short, this potent agent kills cancer cells by inducing oxidative stress.


Ronald Piana: Mundi’s study is the first in the literature to evaluate high-concentrate H2O2 as a topical treatment for cervicofacial cutaneous malignancies. The results have broad health implications for the millions of Americans diagnosed each year with skin cancers, and further indicate that topical H2O2 treatment could be a valuable clinical option for a variety of healthcare professionals including surgeons, dermatologists, and primary care physicians. Therefore, I hold that prior investigative work coupled with findings from Mundi, et al., should be viewed as proof-of-concept in safety and efficacy leading to larger scale evaluation and recognition of topical H2O2 as a treatment option for select carcinomas and, equally important, opening the investigative door into other exciting clinical opportunities.

My concern is that further serious investigation of this cheap and readily available agent, for various reasons beyond the scope of this post, will be ignored or rebuffed by the research and medical communities. To that end, I encourage others in the healthcare community not to let this valuable clinical opportunity pass.

Sunday, September 1, 2024

Gary Stevenson might be redpilling lol


Gary Stevenson taking a bit of a breather as he journeys into redpill land. Looks like he doesn't yet realize just what he's up against. Soon he will come to the same fork in the road that we all do. We will see which one he chooses.

Tuesday, June 18, 2024

All Wars Are Bankster Wars




When they ask, "What do you mean, every single time?" Lol
If you don't own your banks, you don't own anything else.
They've been feeding Whites into the meat grinder for 500 years.
NO "INTEREST". NO "USURY". NO "FRACTIONAL DERPSERVE."
WHITE CHRISTIAN BANKS NOW

Friday, May 31, 2024

Dave Smith Destroys Climate Change




Seriously, all these dumbshit cunts just spout whatever groupthink stupidity they're paid to spout. "Say this retarded nonsense or lose ur job!" And just like their simp husbands they do it. Let the demons loose, these witches deserve everything that's coming to them.

UPDATE: Dave Smith is jewish. Hahahahahaha. Of course. /facepalm

Saturday, May 18, 2024

Men's roles of responsibility and change



Admiral Hyman G. Rickover, known as the “Father of the Nuclear Navy”, directed the original development of naval nuclear propulsion and controlled its operations for three decades in his position as Director of Naval Reactors.

Rickover is one of only four people who have ever been awarded two Congressional Gold Medals. His substantial legacy of technical achievements includes the United States Navy's continuing record of zero nuclear reactor accidents. Here are some of my favorite quotes attributed to him.

Responsibility is a unique concept. You may share it with others, but your portion is not diminished. You may delegate it, but it is still with you. If responsibility is rightfully yours, no evasion, or ignorance or passing the blame can shift the burden to someone else. Unless you can point your finger at the man who is responsible when something goes wrong, then you have never had anyone really responsible.

The man in charge must concern himself with details. If he does not consider them important, neither will his subordinates. Yet “the devil is in the details.” It is hard and monotonous to pay attention to seemingly minor matters. In my work, I probably spend about ninety-nine percent of my time on what others may call petty details. Most managers would rather focus on lofty policy matters. But when the details are ignored, the project fails. No infusion of policy or lofty ideals can then correct the situation.

Be ever questioning. Ignorance is not bliss. It is oblivion. You don't go to heaven if you die dumb. Become better informed. Learn from others' mistakes. You will not live long enough to make them all yourself.

Avoid over-coordination. We have all observed months long delays caused by an effort to bring all activities into complete agreement with a proposed policy or procedure. While the coordinating machinery is slowly grinding away, the original purpose is often lost. The essence of the proposals is being worn down as the persons most concerned impatiently await the decision. The process has been aptly called “coordinating to death.”

In greek mythology, Antaeus was a giant who was strong as long as he had contact with the earth. When he was lifted from the earth he lost strength. So it is with engineers. They must not become isolated from the real world. Human experience shows that people, not organizations or management systems, get things done.

Do not regard loyalty as a personal matter. A greater loyalty is one to the Navy or to the Country. When you know you are absolutely right, and when you are unable to do anything about it, complete military subordination to rules becomes a form of cowardice.

Free discussion requires an atmosphere unembarrassed by any suggestion of authority or even respect. If a subordinate always agrees with his superior he is a useless part of the organization. In this connection there is a story of Admiral Sims when he was on duty in London in World War I. He called a conscientious hard-working officer in to him to explain why he was dissatisfied with the officer's work. The officer blushed and stammered when Sims pointed out that in all the time they had been working together the officer had never once disagreed with Sims.

One must create the ability in his staff to generate clear, forceful arguments for opposing viewpoints as well as for their own. Open discussions and disagreements must be encouraged, so that all sides of an issue are fully explored.

To doubt one's own first principles is the mark of a civilized man. Don't defend past actions; what is right today may be wrong tomorrow. Don't be consistent; consistency is the refuge of fools.

Sit down before fact with an open mind. Be prepared to give up every preconceived notion. Follow humbly wherever and to whatever abyss nature leads or you learn nothing. Don’t push out figures when facts are going in the opposite direction.

All men are by nature conservative but conservatism in the military profession is a source of danger to the country. One must be ready to change his line sharply and suddenly, with no concern for the prejudices and memories of what was yesterday. To rest upon formula is a terrible slumber that, if prolonged, means death.

- c/o Stephen Moretto, LCS Production Manager at Naval Sea Systems Command (NAVSEA)


Tuesday, April 9, 2024

RFK BigPharma and BigAg poisoning our kids




We simply cannot stress enough that the US government is threatening to regulate AI while Americans are being poisoned from every single direction. Everywhere you look, there is some new poison entering the bodies of Americans. Pharma cannot be regulated. Big agriculture cannot be regulated. Petrochemical companies cannot be regulated.

1960s ― Polychlorinated biphenyls (PCBs), branded as “Aroclor” by Monsanto. Used in coolants, lubricants, hydraulic fluids, paints, sealants, adhesives, and coatings for electrical cables.

Monday, April 1, 2024

ShadowGlades 2 | Leonardo AI



Concept Art: Midjourney AI
Image Enhancement: Magnific AI
Video Transformation: RunwayML
Editing: Capcut
Final Upscaling 4K 60 fps: TopazAI

The source of aggression is insecurity, as we are all aware that our position in life is never secure. So people feel helpless, and often become aggressive on a personal and social level. We can chase external achievements, that's fine, even encouraged, but true goodness comes from introspection.